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Matchup summary

The White Sox take on the Cardinals in MLB action on Friday, September 11 at 8:16 PM ET. The consensus line has White Sox favored at -110 on the moneyline with the total sitting at 8.5. Market win probability leans White Sox at 50.5%. Odds from 8 books, line movement, sharp money splits, and every graded Locksmith pick on this matchup update on this page through game time.

More on this matchup: White Sox betting trends · Cardinals betting trends · all MLB games

White Sox vs Cardinals Prediction, Odds & Picks — Sep 11, 2026 | Locksmith