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Matchup summary

The Pirates take on the Cubs in MLB action on Friday, September 11 at 2:21 PM ET. Pirates are getting +160 on the moneyline with the total at 8.5. Market win probability leans Cubs at 63.7%. Odds from 6 books, line movement, sharp money splits, and every graded Locksmith pick on this matchup update on this page through game time.

More on this matchup: Pirates betting trends · Cubs betting trends · all MLB games

Pirates vs Cubs Prediction, Odds & Picks — Sep 11, 2026 | Locksmith