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Matchup summary

The Brewers take on the Pirates in MLB action on Wednesday, September 16 at 6:41 PM ET. The consensus line has Brewers favored at -136 on the moneyline with the total sitting at 7.5. Market win probability leans Brewers at 55.9%. Odds from 7 books, line movement, sharp money splits, and every graded Locksmith pick on this matchup update on this page through game time.

More on this matchup: Brewers betting trends · Pirates betting trends · all MLB games

Brewers vs Pirates Prediction, Odds & Picks — Sep 16, 2026 | Locksmith