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Matchup summary

The Diamondbacks take on the Rockies in MLB action on Tuesday, September 22 at 8:41 PM ET. The consensus line has Diamondbacks favored at -195 on the moneyline with the total sitting at 11. Market win probability leans Diamondbacks at 63.4%. Odds from 5 books, line movement, sharp money splits, and every graded Locksmith pick on this matchup update on this page through game time.

More on this matchup: Diamondbacks betting trends · Rockies betting trends · all MLB games

Diamondbacks vs Rockies Prediction, Odds & Picks — Sep 22, 2026 | Locksmith