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Matchup summary

The Rays take on the Yankees in MLB action on Tuesday, September 22 at 7:06 PM ET. Rays are getting +115 on the moneyline with the total at 6.5. Market win probability leans Yankees at 55.2%. Odds from 5 books, line movement, sharp money splits, and every graded Locksmith pick on this matchup update on this page through game time.

More on this matchup: Rays betting trends · Yankees betting trends · all MLB games

Rays vs Yankees Prediction, Odds & Picks — Sep 22, 2026 | Locksmith