Matchup summary

The Lions take on the Bills in NFL action on Thursday, September 17 at 8:15 PM ET. Lions are getting +138 on the moneyline with the total at 52.5. Market win probability leans Bills at 59.9%. Odds from 7 books, line movement, sharp money splits, and every graded Locksmith pick on this matchup update on this page through game time.

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