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Matchup summary

The Seahawks take on the Cardinals in NFL action on Sunday, September 20 at 4:25 PM ET. The consensus line has Seahawks favored at -550 on the moneyline with the total sitting at 44.5. Market win probability leans Seahawks at 81.9%. Odds from 3 books, line movement, sharp money splits, and every graded Locksmith pick on this matchup update on this page through game time.

More on this matchup: Seahawks betting trends · Cardinals betting trends · all NFL games

Seahawks vs Cardinals Prediction, Odds & Picks — Sep 20, 2026 | Locksmith