Matchup summary

The Chargers take on the Bills in NFL action on Sunday, September 27 at 1:00 PM ET. Chargers are getting +185 on the moneyline with the total at 49.5. Market win probability leans Bills at 72.9%. Odds from 7 books, line movement, sharp money splits, and every graded Locksmith pick on this matchup update on this page through game time.

More on this matchup: Chargers betting trends · Bills betting trends · all NFL games