Matchup summary

The Cardinals take on the 49ers in NFL action on Sunday, September 27 at 4:05 PM ET. Cardinals are getting +375 on the moneyline with the total at 48.5. Market win probability leans 49ers at 81.3%. Odds from 7 books, line movement, sharp money splits, and every graded Locksmith pick on this matchup update on this page through game time.

More on this matchup: Cardinals betting trends · 49ers betting trends · all NFL games