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Matchup summary

The Padres take on the Dodgers in MLB action on Tuesday, September 22 at 10:11 PM ET. Padres are getting +102 on the moneyline with the total at 8.5. Market win probability leans Dodgers at 53%. Odds from 5 books, line movement, sharp money splits, a market confluence table (money vs tickets, line movement and which side holds the money, with the record of past games that showed the same reading), and every graded Locksmith pick on this matchup update on this page through game time.

More on this matchup: Padres betting trends · Dodgers betting trends · all MLB games

Padres vs Dodgers Prediction, Odds & Picks — Sep 22, 2026 | Locksmith