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49ers @ Colts

49ers
4827
Final
Colts
Mon, Dec 22, 2025, 8:15 PM ET · NFL 2025 week 16
Closing · ML -221 · SPR +4.5 · O/U 46.5

Archived game: closing numbers from Action Network's consensus at kickoff. Live odds, picks and the confluence table only run on games still on the slate.

Matchup summary

Final: 49ers beat the Colts 48-27 on the road. The market closed with 49ers at -221 on the moneyline and the total at 46.5. This was an NFL 2025 week 16 game. The closing betting splits (tickets vs money), the opening line and the movement into kickoff are below.

More on this matchup: 49ers betting trends · Colts betting trends · all NFL games

49ers vs Colts betting splits

Where was the money on 49ers vs Colts?

MarketSideTicketsMoneyClosing line / odds
Spread49ers60%55%-4.5 (-106)
Colts40%45%+4.5 (-113)
TotalOver64%68%O 46.5 (-102)
Under36%32%U 46.5 (-114)
Moneyline49ers83%74%-221
Colts17%26%+185

60% of spread tickets and 55% of spread money were on the 49ers, so the 49ers drew more tickets than money and the average Colts bet was larger.

64% of total tickets and 68% of total money were on the over, so the average over bet was larger than the average under bet.

83% of moneyline tickets and 74% of moneyline money were on the 49ers, so the 49ers drew more tickets than money and the average Colts bet was larger.

Line movement

What was the closing line for 49ers vs Colts?

MarketOpeningClosingMove
Spread (Colts)+3+4.5+1.5
Total46.546.50

The 49ers opened -3 and closed -4.5, a 1.5-point move toward the 49ers.

The total opened 46.5 and closed 46.5: it has not moved.

Why the line moved

Why did the 49ers vs Colts line move?

The spread moved 1.5 points toward the 49ers (Colts +3 to Colts +4.5), the side holding 55% of the spread money and 60% of the tickets, so the line and the money went the same way. The total did not move from its opening number (46.5) even with 68% of the total money on the over. Splits describe where the money sits, not what will happen.

Across 822 NFL games (2023 week 5 through 2026 week 2, Action Network closing splits), the side with a larger money share than ticket share covered the spread 50.0% of the time (384-384-13) and hit the total 50.8% (396-383-6); break-even at -110 is 52.4%. Splits describe where the money sits, not what will happen.

Read more

49ers vs Colts Final Score, Closing Odds & Betting Splits — Dec 22, 2025 | Locksmith